Table 3. . Economic outcomes of probabilistic sensitivity analyses for EmboTrap, Trevo and Solitaire.
| Country and device | Short-term cost Mean (95% CrI) |
Long-term cost Mean (95% CrI) |
Total cost Mean (95% CrI) |
Per-patient incremental cost compared with EmboTrap Mean (95% CrI) |
Iterations with cost savings using EmboTrap | Per-patient incremental cost compared with Trevo Mean (95% CrI) |
Iterations with cost savings using Trevo |
|---|---|---|---|---|---|---|---|
| US (USD) | |||||||
| EmboTrap | $65,797 (65,674; 65,920) |
$25,637 (25,607; 25,668) |
$91,434 (91,306; 91,562) |
– | – | – | – |
| Trevo | $68,925 (68,795; 69,054) |
$27,673 (27,639; 27,706) |
$96,597 (96,463; 96,732) |
$5163 (4580; 5747) |
99.62% | – | – |
| Solitaire | $69,729 (69,598; 69,861) |
$28,199 (28,164; 28,233) |
$97,928 (97,790; 98,066) |
$6494 (5900; 7088) |
99.92% | $1331 (722; 1939) |
74.92% |
| Canada (CAD) | |||||||
| EmboTrap | $15,925 (15,896; 15,955) |
$28,576 (28,545; 28,608) |
$44,502 (44,458; 44,546) |
– | – | – | – |
| Trevo | $16,682 (16,651; 16,714) |
$30,174 (30,140; 30,208) |
$46,856 (46,810; 46,903) |
$2354 (2153; 2557) |
99.62% | – | – |
| Solitaire | $16,877 (16,845; 16,909) |
$30,587 (30,552; 30,622) |
$47,464 (47,416; 47,513) |
$2962 (2756; 3169) |
99.92% | $608 (395; 820) |
74.92% |
| UK (GBP) | |||||||
| EmboTrap | £9277 (9259; 9294) |
£11,532 (11,517; 11,547) |
£20,809 (20,785; 20,832) |
– | – | – | – |
| Trevo | £9718 (9699; 9736) |
£12,772 (12,755; 12,789) |
£22,489 (22,464; 22,515) |
£1680 (1571; 1790) |
99.62% | – | – |
| Solitaire | £9831 (9813; 9850) |
£13,092 (13,074; 13,110) |
£22,923 (22,896; 22,949) |
£2114 (2002; 2226) |
99.92% | £434 (317; 550) |
74.92% |
| Sweden (SEK) | |||||||
| EmboTrap | 140,212kr (139,952; 140,472) |
204,003kr (203,721; 204,286) |
344,215kr (343,819; 344,622) |
– | – | – | – |
| Trevo | 146,883kr (146,600; 147,154) |
228,810kr (228,482; 229,126) |
375,681kr (375,251; 376,122) |
31,466kr (29,623; 33,309) |
99.62% | – | – |
| Solitaire | 148,590kr (148,319; 148,873) |
235,209kr (234,870; 235,548) |
383,810kr (383,358; 384,263) |
39,584kr (37,685; 41,484) |
99.92% | 8118kr (6139; 10,097) |
74.92% |
| Germany (EUR) | |||||||
| EmboTrap | €11,505 (11,484; 11,527) |
€11,274 (11,257; 11,292) |
€22,779 (22,751; 22,808) |
– | – | – | – |
| Trevo | €12,052 (12,029; 12,075) |
€12,886 (12,867; 12,906) |
€24,938 (24,908; 24,969) |
€2159 (2028; 2290) |
99.62% | – | – |
| Solitaire | €12,193 (12,170; 12,216) |
€13,303 (13,282; 13,323) |
€25,495 (25,463; 25,527) |
€2716 (2581; 2851) |
99.92% | €557 (417; 697) |
74.92% |
| France (EUR) | |||||||
| EmboTrap | €8356 (8341; 8372) |
€10,369 (10,358; 10,381) |
€18,726 (18,706; 18,745) |
– | – | – | – |
| Trevo | €8754 (8737; 8770) |
€10,806 (10,794; 10,818) |
€19,560 (19,539; 19,580) |
€834 (745; 923) |
99.62% | – | – |
| Solitaire | €8856 (8839; 8872) |
€10,919 (10,907; 10,931) |
€19,775 (19,754; 19,796) |
€1049 (959; 1139) |
99.92% | €215 (123; 307) |
74.92% |
| Italy (EUR) | |||||||
| EmboTrap | €8320 (8304; 8336) |
€5224 (5217; 5231) |
€13,544 (13,527; 13,561) |
– | – | – | – |
| Trevo | €8715 (8699; 8732) |
€5762 (5754; 5770) |
€14,477 (14,459; 14,496) |
€934 (855; 1013) |
99.62% | – | – |
| Solitaire | €8817 (8801; 8834) |
€5901 (5893; 5909) |
€14,718 (14,699; 14,737) |
€1174 (1094; 1255) |
99.92% | €241 (158; 324) |
74.92% |
| Spain (EUR) | |||||||
| EmboTrap | €9167 (9150; 9184) |
€19,226 (19,196; 19,256) |
€28,393 (28,358; 28,428) |
– | – | – | – |
| Trevo | €9603 (9585; 9621) |
€22,025 (21,991; 22,060) |
€31,628 (31,589; 31,668) |
€3235 (3068; 3402) |
99.59% | – | – |
| Solitaire | €9714 (9696; 9733) |
€22,742 (22,707; 22,778) |
€32,456 (32,416; 32,497) |
€4063 (3893; 4234) |
99.92% | €828 (648; 1009) |
73.98% |
| Belgium (EUR) | |||||||
| EmboTrap | €12,450 (12,426; 12,473) |
€13,788 (13,769; 13,806) |
€26,237 (26,206; 26,268) |
– | – | – | – |
| Trevo | €13,042 (13,017; 13,066) |
€15,411 (15,389; 15,432) |
€28,452 (28,419; 28,485) |
€2215 (2073; 2357) |
99.62% | – | – |
| Solitaire | €13,194 (13,169; 13,219) |
€15,830 (15,807; 15,852) |
€29,024 (28,989; 29,058) |
€2786 (2640; 2932) |
99.92% | €571 (420; 723) |
74.92% |
| The Netherlands (EUR) | |||||||
| EmboTrap | €20,267 (20,230; 20,305) |
€17,879 (17,856; 17,902) |
€38,146 (38,102; 38,191) |
– | – | – | – |
| Trevo | €21,235 (21,196; 21,274) |
€19,775 (19,749; 19,801) |
€41,010 (40,962; 41,058) |
€2864 (2658; 3070) |
99.64% | – | – |
| Solitaire | €21,478 (21,438; 21,517) |
€20,251 (20,224; 20,278) |
€41,729 (41,680; 41,778) |
€3583 (3373; 3793) |
99.90% | €719 (502; 936) |
73.67% |
Probabilistic analyses were based on parametric Monte Carlo simulations with 10,000 iterations.
Results for Germany represent both 2023 and 2024 values due to the use of 2024 physician fees to calculate long-term costs.
CAD: Canadian dollar; CrI: Credible interval; EUR: Euro; GBP: Great Britain Pound; SEK: Swedish krona; USD: United States dollar.