Table 2.

Main effects models for association between the presence of MetS and current depressive symptom severity (total PHQ-9 scores), current depressive symptoms (yes/no), and antidepressant use.

MetS (yes/no)
Exposure group	OR (95% CI)	p-value	aOR (95% CI)	p-value
Total PHQ-9 scores1a	1.05 (1.04, 1.06)	<0.001	1.04 (1.02, 1.05)	<0.001
Antidepressant use - yes1b	1.70 (1.46, 1.97)	<0.001	1.24 (1.03, 1.50)	0.025
Depressive symptoms - yes2a	1.78 (1.51, 2.10)	<0.001	1.42 (1.17, 1.73)	0.001
Antidepressant use - yes2b	1.70 (1.46, 1.97)	<0.001	1.31 (1.09, 1.57)	0.004

OR unadjusted odds ratio, aOR adjusted odds ratio, CI confidence interval, the reference level for depressive symptoms is “no”. 1aCovariates in adjusted models include all 15 pre-selected covariates and antidepressant use. 1bCovariates in adjusted models include all 15 pre-selected covariates and depressive symptom severity (total PHQ-9 scores). 2aCovariates in adjusted models include all 15 pre-selected covariates and antidepressant use. 2bCovariates in adjusted models include all 15 pre-selected covariates and depressive symptoms (yes/no). p-values < 0.05 denote statistical significance.