Table 3.
Main effects models for association between the presence of MetS and antidepressant type.
| MetS (yes/no) | ||||
|---|---|---|---|---|
| Antidepressant type | OR (95% CI) | p-value | aOR (95% CI) | p-value |
| SSRIs | 1.53 (1.24, 1.88) | <0.001 | 1.18 (0.92, 1.53) | 0.190 |
| SNRIs | 1.70 (1.12, 2.57) | 0.013 | 1.24 (0.80, 1.93) | 0.331 |
| TCA | 3.49 (2.29, 5.32) | <0.001 | 2.27 (1.31, 3.93) | 0.004 |
| Atypical antidepressants | 1.44 (1.02, 2.04) | 0.040 | 1.08 (0.73, 1.61) | 0.694 |
| More than one type | 2.03 (1.46, 2.83) | <0.001 | 1.19 (0.84, 1.69) | 0.317 |
OR unadjusted odds ratio, aOR adjusted odds ratio, CI confidence interval, the reference level for antidepressant type is “non-user”. Covariates in adjusted models include all 15 pre-selected covariates and depressive symptom severity (total PHQ-9 scores). p-values < 0.05 denote statistical significance.