Figure 5.

Electrophoretic analysis of DNA from apoptotic cells. DNA extracts can be purified, run on an agarose gel, and stained with fluorescent ethidium bromide. DNA from apoptotic cells (aged blood polymorphs in this case) forms a distinctive laddering pattern as a result of endonuclease cleavage (lane 1). Lane 2, DNA isolated from necrotic cells; lanes and 6, no sample; lanes 3 and 4, DNA immediately after isolation (before treatment); lane 7, standard DNA molecular weight markers. Band sizes are in kDa.