Table 2.
Group A–D | Xho-I | Repeat region | 30 bp deletion | Number of cases | |
HD | A | + | 4+ | – | 9 |
A | + | 3, 6 | – | 2 | |
A* | – | 4+ | – | 1 | |
A* | + | 4+ | + | 1 | |
B | + | 4–6 | – | 3 | |
B* | – | 4, 5 | – | 4 | |
B* | + | 5 | + | 1 | |
B* | + | 5 | 12 bp | 1 | |
C | + | 3–6 | + | 10 | |
D | – | 3 | – | 1 | |
UG | + | 4+ | – | 1 | |
IM | A | + | 4+ | – | 2 |
B | + | 6 | – | 1 | |
C | + | 5, 6 | + | 3 | |
D | – | 2–4 | – | 3 | |
UG | – | 5 | + | 1 |
Group A–D, grouping of the isolates based on sequence analysis of the LMP-1 gene and part of the promoter of sequenced isolates (groups A–D as defined in the result section).
Xho-I, presence (+) or loss (–) of the Xho-I restriction site.
Repeat region, the number of perfect 33 bp repeats in the LMP-1 repeat region; + indicates a repeat region identical to the prototype EBV strain B95.8.11
30 bp deletion, absence (–) or presence (+) of the 30 bp deletion (del-LMP-1).
*These cases contained additional mutations affecting the Xho-I restriction site or contained the 30 bp deletion (one case with a unique 12 bp deletion) but otherwise had a pattern of single base mutations similar to group A or group B.
UG, ungrouped cases.