Table 3.
Expression of E-cadherin and β-catenin in lobular carcinoma in situ (LCIS) and adjacent invasive areas
| LCIS | Invasive | ||||
| Patient | E-cadherin | β-Catenin | E-cadherin | β-Catenin | Histology |
| 1 | + | + | + | + | ILC |
| 2 | ND | ND | + | + | IDC |
| 3 | – | – | – | – | IDC |
| 4 | – | ND | – | – | ILC |
| 5 | – | – | + | + | IDC |
| 6 | H | – | H | + | IDC |
| 7 | ND | ND | ND | ND | ILC |
| 8 | – | – | – | – | ILC |
| 9 | ND | – | – | – | ILC |
| 10 | ND | ND | H | ND | ILC |
| 11 | – | – | ND | ND | ILC |
| 12 | – | – | – | – | IDC |
| 13 | – | ND | H | + | IDC |
| 14 | ND | – | ND | – | IDC |
| 15 | H | – | + | – | IDC |
| 16 | – | – | – | – | ILC |
| 17 | – | – | H | H | IDC |
| 18 | – | – | – | – | ILC |
| 19 | – | – | – | – | ILC |
| 20 | – | – | – | – | ILC |
| 21 | – | – | – | – | ILC |
Staining: +, membranous staining; –, no detectable membranous staining; H, limited membranous staining.
IDC, infiltrating ductal carcinoma; ILC, infiltrating lobular carcinoma; ND, not determined owing to lack of tissue availability.