Figure 6.

In vivo growth curves of tumours induced by G59W and G59W540 glioma cells. Two complete animal experiments were performed with G59W and G59W540 cells; 5 × 10⁶ cells were injected into the right hind limb of each mouse with 1/1 medium and metri-gel. Tumour growth was assessed by twice weekly measurements with a caliper; 10 animals were injected in each group. For the G59W cells, all 10 developed tumours. For the G59W540 cells, only three of the 10 animals developed tumours. In each group, the mean size was determined by averaging measurements from the animals that grew tumours. For the second in vivo experiment (data not shown), eight of the 10 animals injected with G59W cells grew tumours, but four of these regressed by the final measurement date (day 53). Of the 10 animals injected with G59W540 cells, only four grew tumours, which were all small.