Table 1.

Characteristics of human acid phosphatases

Human acid phosphatase (AP)	Tissue/cells cells of origin	M (kDa)	Gel band	Chromosome	Amino acid sequence	Amino acid homology	Tartrate resistance	Fluoride resistance4
Lysosomal (LAP)	Most cells1	1001	32	111	4233	50% PAP3	–	+
Prostatic (PAP)	Prostate gland, brain, spleen, liver, platelets	1003	2b5	33	3453	50% LAP3	–	+
Erythrocytic (EAP)	Erythrocytes, many cell types	186	12	27	1578	None known	+	+
Macrophage (MAP)	Macrophages of liver, spleen, lung	379	510	199	3259	High with OcAP12	+	+
Osteoclastic (OcAP)	Osteoclasts of bone	3711	510	199	3259	High with MAP12	+	–

Gel band refers to the relative position of acid phosphatase after its migration towards the cathode in acidic polyacrylamide gel electrophoresis.¹⁰,¹³

M, molecular mass.