Table 2.
Clinical importance of human acid phosphatases
| Human acid phosphatase (AP) | Clinical and laboratory importance |
| Lysosomal (LAP) | LAP deficiency: an inherited autosomal recessive disorder affecting metabolism14 |
| Prostatic (PAP) | Serum marker for cancer of the prostate15 |
| Semen marker used in forensics for cases of sexual abuse16 | |
| Erythrocytic (EAP) | Increased susceptibility to developmental disturbances and haemolytic favism with certain alleles8 |
| Paternity testing17 | |
| Macrophage (MAP) | Gaucher's disease: an inborn error of cerebroside metabolism18,19 |
| Osteoclastic (OcAP) | Metastasis to the bone20,21 |
| Bone resorption conditions22 |