Figure 2.

Expression, as measured by in situ antisense RNA hybridisation, of Wnt 2 (top row) and bone morphogenetic protein 6 (BMP6; bottom row) in normal colon (left two columns, original magnifications, ×40 and ×100) and colon cancer (right column, original magnification, ×100) from the same individual. The dark purple colouration indicates positive hybridisation. The pink staining is the result of the FAST red dye used to reveal tissue architecture. Hybridisation for a specific probe on normal and cancer tissues was performed concomitantly, under identical conditions, and with freshly prepared probe.