Figure 4.

In situ hybridisation of KLK8 mRNA in the lesional skin of squamous cell carcinoma (SCC). (A) Low power micrograph showing haematoxylin and eosin staining of highly differentiated SCC. (B) Dark field micrograph showing silver grains around horn pearls (asterisks). (C) And (D) are high power magnifications of the boxed area in (A) showing intense signals for KLK8 mRNA. (A) And (C) are bright field micrographs of skin sections counterstained by haematoxylin and eosin; (B) and (D) are dark field micrographs of the same fields shown in (A) and (C), respectively. Scale bars: (A,B), 1 mm; (C,D), 400 μm. hp, horn pearl.