Table 4.
Expression patterns of E-cadherin, β catenin, γ catenin, and ezrin in Wilms’s tumours and staining intensity using immunohistochemistry
| E-cadherin | β Catenin | γ Catenin | Ezrin | |||||||||
| Tumour group | Ep | Bl | Str | Ep | Bl | Str | Ep | Bl | Str | Ep | Bl | Str |
| Primary tumours | –/++ | –/++ | – | –/+++ | +++ | – | + | –/++ | – | + | –/++ | – |
| Paired metastatic tumours | –/+++ | –/++ | – | +/++++ | +/++++ | – | +/++ | –/+ | – | +/++ | –/++ | – |
| Primary (non-metastatic) tumours | –/+++ | –/+ | – | –/++++ | ++/++++ | – | +/+++ | –/++ | – | ++++ | ++/++++ | – |
| Unpaired metastatic tumours | –/+++ | –/++ | – | ++/++++ | +/++++ | – | +/+++ | –/+ | – | –/+++ | ++/+++ | – |
Each column shows the average range for all the tumours. Results are shown for all the tumours listed in table 1 ▶. Semiquantitative scale (relative to normal human kidney staining): –, negligible; +, weak; ++, moderate; +++, strong; ++++, very strong.
Bl, blastemal; Ep, epithelial; Str, stromal.