Skip to main content
. 2003 Dec;56(6):336–341. doi: 10.1136/mp.56.6.336

Figure 1.

Figure 1

Cyclin D1 and β catenin expression as assessed by immunohistochemistry in carcinoma of ampulla of Vater. Moderately differentiated adenocarcinoma showing heterogeneous (A) nuclear cyclin D1 expression and (B) β catenin expression. This case shows a similar distribution pattern of cyclin D1 and β catenin staining (original magnification, ×100). This patient had a mutated CTNNB-1 gene and a wild-type k-ras gene. Well differentiated adenocarcinoma showing a similar distribution pattern for (C) cyclin D1 and (D) β catenin staining at the invasive edge of the tumour (original magnification, ×100). This patient had a mutated CTNNB-1 gene and a mutated k-ras gene. Moderately differentiated adenocarcinoma cells showing (E) diffuse nuclear cyclin D1 expression and (F) membranous β catenin expression (original magnification, ×100). This patient had a wild-type CTNNB-1 gene and a mutated k-ras gene.