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. 2025 Feb 24;16(13):5623–5631. doi: 10.1039/d4sc08521c

Table 2. Optimization of the cross-coupling.

graphic file with name d4sc08521c-u2.jpg
# Deviations from stand. cond. Y. of 3,a (%)
1 None 92 (91)b
2 Open to air 87
3 455 nm LED 82
4 4CzIPN as PC (455 nm LED) 80
5 Without DME 76
6 L2 as the ligand 76
7 No phthalimide 64
8 No NiCl2·diglyme 0
9 No L1 <5
10 No PC <5
11 No light 0
a

Determined by 1H NMR with CH2Br2 as an internal standard.

b

Isolated yield.