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. 2024 Nov 25;111(5):e324553. doi: 10.1136/heartjnl-2024-324553

Table 4. Correlations between V̇O2peak and biochemistry/imaging parameters.

V̇O2peak Age-normalised/Sex-normalised V̇O2peak
N Rho P value Rho P value
FEV1 41 0.468 0.002 0.491 0.001
Biochemistry
 Creatinine 42 −0.118 0.458 −0.165 0.295
 HS troponin-I 32 −0.478 0.006 −0.397 0.025
 NT-proBNP 42 −0.662 <0.001 −0.626 <0.001
 ACR 41 −0.305 0.053 −0.290 0.066
 Cholesterol 42 −0.244 0.120 −0.243 0.122
 Low-density lipoprotein 33 −0.228 0.201 −0.231 0.195
 Haemoglobin 42 −0.147 0.352 −0.102 0.521
 C reactive protein 36 −0.278 0.101 −0.377 0.023
 White cell count 42 −0.308 0.047 −0.313 0.044
 Neutrophil count 42 −0.427 0.005 −0.404 0.008
 Lymphocyte count 42 0.371 0.015 0.347 0.024
 Neutrophil-Lymphocyte ratio 42 −0.536 <0.001 −0.499 <0.001
Cardiac magnetic resonance imaging parameters
 LV EDVi 37 0.338 0.041 0.222 0.187
 LV ESVi 37 0.270 0.106 0.147 0.386
 LV SVi 36 0.328 0.051 0.240 0.159
 LV Mi 37 −0.340 0.039 −0.321 0.053
 LV EF 37 −0.269 0.107 −0.181 0.285
 RV EDVi 36 0.343 0.041 0.294 0.082
 RV ESVi 36 0.108 0.529 0.089 0.607
 RV SVi 35 0.433 0.009 0.456 0.006
 RV EF 36 −0.074 0.667 −0.052 0.764
 LA volume 36 −0.237 0.165 −0.183 0.285
 Lowest T1 33 0.046 0.798 0.141 0.433
Transthoracic echocardiography parameters
 TR velocity 19 −0.683 0.001 −0.649 0.003
 LA EDV 37 −0.375 0.022 −0.438 0.007
 LA ESV 37 −0.266 0.111 −0.313 0.059
 LA GCS 37 0.252 0.132 0.288 0.084
 LA GLS 37 0.280 0.093 0.342 0.038
 LA EF 37 0.341 0.039 0.403 0.013
 LA FAC 37 0.338 0.041 0.403 0.013

Correlations between each parameter and both the observed and age-normalised/sex-normalised V̇O2peak are quantified using Spearman’s rank correlation coefficients (rho). Bold p -values are significant at pp<0.05.

ACR, urine albumin to creatinine ratio; EDVi, end-diastolic volume (indexed); EF, ejection fraction; ESVi, end-systolic volume (indexed); FAC, fractional area change; FEV1, forced expiratory volume in 1 s; GCS, global circumferential strain; GLS, global longitudinal strain; HS, high sensitivity; LA, left atrial; LV, left ventricular; Mi, mass indexed; NT-proBNP, N-terminal pro B-type natriuretic peptide; RV, right ventricular; SVi, stroke volume indexed; TR, tricuspid regurgitation; V̇O2peak, peak oxygen uptake