Table 4. Correlations between V̇O2peak and biochemistry/imaging parameters.
| V̇O2peak | Age-normalised/Sex-normalised V̇O2peak | ||||
| N | Rho | P value | Rho | P value | |
| FEV1 | 41 | 0.468 | 0.002 | 0.491 | 0.001 |
| Biochemistry | |||||
| Creatinine | 42 | −0.118 | 0.458 | −0.165 | 0.295 |
| HS troponin-I | 32 | −0.478 | 0.006 | −0.397 | 0.025 |
| NT-proBNP | 42 | −0.662 | <0.001 | −0.626 | <0.001 |
| ACR | 41 | −0.305 | 0.053 | −0.290 | 0.066 |
| Cholesterol | 42 | −0.244 | 0.120 | −0.243 | 0.122 |
| Low-density lipoprotein | 33 | −0.228 | 0.201 | −0.231 | 0.195 |
| Haemoglobin | 42 | −0.147 | 0.352 | −0.102 | 0.521 |
| C reactive protein | 36 | −0.278 | 0.101 | −0.377 | 0.023 |
| White cell count | 42 | −0.308 | 0.047 | −0.313 | 0.044 |
| Neutrophil count | 42 | −0.427 | 0.005 | −0.404 | 0.008 |
| Lymphocyte count | 42 | 0.371 | 0.015 | 0.347 | 0.024 |
| Neutrophil-Lymphocyte ratio | 42 | −0.536 | <0.001 | −0.499 | <0.001 |
| Cardiac magnetic resonance imaging parameters | |||||
| LV EDVi | 37 | 0.338 | 0.041 | 0.222 | 0.187 |
| LV ESVi | 37 | 0.270 | 0.106 | 0.147 | 0.386 |
| LV SVi | 36 | 0.328 | 0.051 | 0.240 | 0.159 |
| LV Mi | 37 | −0.340 | 0.039 | −0.321 | 0.053 |
| LV EF | 37 | −0.269 | 0.107 | −0.181 | 0.285 |
| RV EDVi | 36 | 0.343 | 0.041 | 0.294 | 0.082 |
| RV ESVi | 36 | 0.108 | 0.529 | 0.089 | 0.607 |
| RV SVi | 35 | 0.433 | 0.009 | 0.456 | 0.006 |
| RV EF | 36 | −0.074 | 0.667 | −0.052 | 0.764 |
| LA volume | 36 | −0.237 | 0.165 | −0.183 | 0.285 |
| Lowest T1 | 33 | 0.046 | 0.798 | 0.141 | 0.433 |
| Transthoracic echocardiography parameters | |||||
| TR velocity | 19 | −0.683 | 0.001 | −0.649 | 0.003 |
| LA EDV | 37 | −0.375 | 0.022 | −0.438 | 0.007 |
| LA ESV | 37 | −0.266 | 0.111 | −0.313 | 0.059 |
| LA GCS | 37 | 0.252 | 0.132 | 0.288 | 0.084 |
| LA GLS | 37 | 0.280 | 0.093 | 0.342 | 0.038 |
| LA EF | 37 | 0.341 | 0.039 | 0.403 | 0.013 |
| LA FAC | 37 | 0.338 | 0.041 | 0.403 | 0.013 |
Correlations between each parameter and both the observed and age-normalised/sex-normalised V̇O2peak are quantified using Spearman’s rank correlation coefficients (rho). Bold p -values are significant at pp<0.05.
ACR, urine albumin to creatinine ratio; EDVi, end-diastolic volume (indexed); EF, ejection fraction; ESVi, end-systolic volume (indexed); FAC, fractional area change; FEV1, forced expiratory volume in 1 s; GCS, global circumferential strain; GLS, global longitudinal strain; HS, high sensitivity; LA, left atrial; LV, left ventricular; Mi, mass indexed; NT-proBNP, N-terminal pro B-type natriuretic peptide; RV, right ventricular; SVi, stroke volume indexed; TR, tricuspid regurgitation; V̇O2peak, peak oxygen uptake