Table 1. Compiled case reports of lipid pneumonia secondary to Vicks VapoRub use.

Author, Year	Description of patient use	Symptomatology	Imaging	Biopsy	Treatment	Naranjo score
Cohen & Schoene, 1963	Three years of putting a tablespoon of product in the back of his throat each night for dry throat relief	55-yo white male with history of smoking,presented with one year of dry cough and intermittent substernal chest pain	CXR	Scalene biopsy, Right lower lobectomy	No treatment reported	4
Subramanian et al., 1982	Five years of use in and around nostrils for sinus troubles	61-yo white male farmer, presented with fever, chills, fungal colonization	CXR	Fiberoptic bronchoscopy, transbronchial biopsy	Cessation	4
Gattuso, Reddy & Castelli, 1991	Inhaling for multiples years to relieve asthma symptoms	70-yo female with history of asthma, presented with 10-month history of SOB, hoarseness, and decreased exercise tolerance	CXR, CT	CT-guided FNA biopsy	No treatment reported	4
Kulkarni & Pena, 2012	Regular use at night by applying it inside nose several times per week for years	68-yo white male with history of moderate COPD, 80 pack year smoking history, presented with minimal shortness of breath then, after being lost to follow up, returned a year later with worse dyspnea and cough	CXR, CT, PET	Left upper lobectomy, hilar lymph node resection	Cessation	4
Rangarajan et al., 2012	Inside nostrils at bedtime for several years	40-yo white female presented with shortness of breath on exertion for two years	HRCT	VATS lung biopsy	Cessation(Previously trialed on 1 year of steroids and azathioprine)	4
Martin, 2013	History of use in her nostrils daily as a child and current mineral oil use for constipation	49-yo female presented with cough and dyspnea on exertion for several months became oxygen dependent and resulted in super infection	PET	CT-guided biopsy, open lung biopsy	Cessation, whole lung lavage, lung transplant clinic referral	0
Kamal, Azzi & Elsayegh, 2015	Twenty years applied intranasally to relieve congestion	55-yo male with history COPD, increased cough for 2 years, 93% saturation on room air	CT	Transthoracic FNA	Cessation	3
Cherrez Ojeda et al., 2016	Daily use for 50 years onto chest, palms, feet and aspirated through nose	85-yo female patient with history of allergic rhinitis presenting without respiratory symptoms for routine annual physical exam with elevated CRP	CXR, CT	Thoracic CT density values indicating lipoid mass with improved follow up scan ruling out malignancy	Cessation, intranasal corticosteroids	4
Kilaru et al., 2017	Over a year of external nostril application nightly	23-yo female with 5 year history of chronic rhino-bronchial allergies, presented with cough, dyspnea, and fever for >4 weeks	CXR, HRCT	Fiberoptic bronchoscopy, transbronchial lung biopsy	Oral prednisone for 6 months, continued inhaled corticosteroid and Fluticasone spray	6
Cabri et al., 2017	Daily intranasal application for over 4 months	57-yo female presented with dry cough over 4 months	CT	Computed tomography (CT) of the chest showed foci of consolidation and ground-glass attenuation in gravity-dependent segments of the right lower lobe.	Cessation	4
Sargi et al., 2021	Continuous use for many years	79-yo female who presented with non-productive cough and dyspnea on exertion for over a month, requiring supplemental oxygen.	CXR, CT	Bronchoalveolar lavage sample	Steroids without improvement, No other treatment reported	2