Table 2.
Univariable Cox regression of study cohorts.
| Univariable cox | Training cohort | Testing cohort | ||
|---|---|---|---|---|
| p-value | HR (95% CI) | p-value | HR (95% CI) | |
| Male vs. Female | 0.503 | 0.085 | ||
| Age > 65 vs. Age < 65 | 0.038 | 1.89(1.03–3.47) | 0.528 | |
| T3/T4 vs. T1/T2 | 0.027 | 1.87(1.07–3.28) | 0.023 | 2.44(1.13–5.24) |
| N2/N3 vs. N0/N1 | < 0.001 | 3.04(1.57–5.88) | 0.918 | |
| RT alone vs. CCRT | 0.186 | 0.751 | ||
| Induction Chemo (IC) before RT vs. w/o IC | < 0.001 | 3.07(1.81–5.21) | 0.065 | |
| Adjuvant Chemo (AC) after RT vs. w/o AC | 0.150 | 0.359 | ||
| BMI > 25 vs. BMI < 25 | 0.936 | 0.540 | ||
| ECOG = 1 vs. ECOG = 0 | 0.062 | 3.84(0.92–15.94) | 0.519 | |
| EBV DNA Positive vs. EBV DNA Negative | 0.276 | 0.606 | ||
| PPP > 0.319 vs. PPP < 0.319 | < 0.001 | 7.32(3.87–13.86) | < 0.001 | 2.66(1.72–4.11) |
| Post-RT pWL > 5% vs. post-RT pWL < 5% | 0.232 | 0.440 | ||
| Post-RT pWL > 10% vs. post-RT pWL < 10% | 0.962 | 0.044 | 1.46(1.01–2.14) | |
Significant values are in [bold].