Table 1.
Plasma TSH, T4, and T3 in Control and TPO-TSC2KO Male Mice
| Age (months) | TSH (ng/mL) | Total T4 (ng/mL) | Total T3 (ng/mL) |
|---|---|---|---|
| 2 | |||
| Control | 37.61 ± 8.76 (5) | 74.2 ± 3.3 (9) | 2.12 ± 0.04 (9) |
| TPO-TSC2KO | 46.4 ± 10 (6) | 70.2 ± 3.5 (8) | 1.99 ± 0.08 (8) |
| 6 | |||
| Control | 39.5 ± 9.5 (10) | 93.3 ± 6.3 (4) | 0.88 ± 0.008 (4) |
| TPO-TSC2KO | 82.8 ± 17.7* (11) | 76.2 ± 5.1 p = 0.07 (8) | 0.89 ± 0.008 (7) |
| 12 | |||
| Control | 69.2 ± 8.2 (4) | 106.5 ± 14.6 (7) | 1.09 ± 0.043 (10) |
| TPO-TSC2KO | 203.6 ± 42.4* (8) | 75.7 ± 4.7 p = 0.08 (6) | 1.03 ± 0.043 (8) |
Data are shown as mean ± SEM.
Sample sizes are given in parentheses.
*p < 0.05 vs. littermate controls at the same age determined by the unpaired two-tailed Student’s t-test.