Table 3. Scope of Aldehydes (1 mmol scale) in CTAB 2% and Tween 80 2% for 24 h^a.

						Yield(%)b
Entry	Aldehyde	X	W	Z	T(°C)	CTAB				Tween 80
1	H	CH	CH	-	25	3a	65	4a	10	3a	84	4a	0
2	4-AcNH	CH	CH	-	25	3b	79	4b	0	3b	85	4b	0
3	4-CH3	CH	CH	-	25	3c	80	4c	8	3c	78	4c	0
4	4-OCH3	CH	CH	-	25	3d	82	4d	9	3d	34	4d	0
5	4-OCH3	CH	CH	-	45	3d	-	4d	-	3d	66	4d	0
6	2-OCH3	CH	CH	-	25	3e	59	4e	0	3e	40	4e	0
7	2,6-diOCH3	CH	CH	-	25	3f	90	4f	0	3f	59	4f	0
8	2,6-diOCH3	CH	CH	-	45	3f	-	4f	-	3f	93	4f	0
9	4-OHc	CH	CH	-	25	3g	37	4g	0	3g	27	4g	0
10	4-OHc	CH	CH	-	45	3g	39	4g	0	3g	21	4g	0
11	4-Br	CH	CH	-	25	3h	82	4h	0	3h	30	4h	0
12	4-Br	CH	CH	-	45	3h	-	4h	-	3h	90	4h	0
14	3-Br	CH	CH	-	25	3i	90	4i	0	3i	76	4i	0
15	2-Br	CH	CH	-	25	3j	55	4j	12	3j	68	4j	0
16	2-Br	CH	CH	-	45	3j	53	4j	19	3j	84	4j	0
16	4-NO2	CH	CH	-	25	3k	69	4k	12	3k	87	4k	0
17	4-NO2	CH	CH	-	45	3k	73	4k	15	3k	-	4k	-
18	4-CN	CH	CH	-	25	3l	66	4m	0	3m	98	4m	0
19	4-COOH	CH	CH	-	25	3m	70	4l	0	3l	0	4l	0
20	4-COOCH3	CH	CH	-	25	3n	28d	4n	0	3n	11	4n	0
21	-	CH	N	-	25	3o	0	4o	23	3o	8	4o	21
22	-	N	CH	-	25	3p	14	4p	2	3p	47	4p	10
23	-	-	-	S	25	3q	83	4q	12	3q	69	4q	0
24	-	-	-	O	25	3r	54	4r	0	3r	49	4r	0
25	-	-	-	NH	25	3s	31	4s	0	3s	71	4s	0

^aReaction conditions: 5 mL vial, benzaldehyde (1 mmol), acetophenone (1 mmol), NaOH (1 equiv), surfactant solution (1 mL), rt or 45 °C, 24 h.

^bIsolated yield.

^c2 equiv of NaOH were used.

^d29% of the derivative acid was also isolated.