Figure 2.

Cerebellar granule cells exhibit increased sensitivity to oxidative challenge. Cell cultures were treated as indicated with either 50 or 100 μM menadione for 1 h and viability was assessed after 0, 2, 6 and 24 h. Untreated cultures exhibited viable percents >95. Percent viable = 100 × the number of cells that exclude trypan blue dye/total cell number.