Figure 5. Most Informative Genomes in the Search for Conservation of Target Motif of SH3 Domains.

We created all possible combinations of two or more genomes of our set of ten genomes. For each combination we calculated the highest accuracy obtained for 11 windows of coverage from 15% to 70% at intervals of 5%. We then calculated the average frequency, over all coverage windows, of each individual species in all groups of genomes, in the combinations of genomes scoring within the 20% highest accuracy values and in the combinations scoring in the lowest 20% values of accuracy. We then used a t-test to determine, for each species, whether the average frequencies within the highest and lowest combinations were significantly different from the frequency in all possible combinations. *, p < 0.05; **, p < 0.001.