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(A) This figure corresponds to the simulation of mutant Ala217Ser. The movement of the lids very similar to those in the wild-type lipase. Thus, despite the mutation, the lids are able to close in an aqueous environment.
(B) Here, the simulated structure is a mutant in Phe214Ser.
Red, lid1 RMSD; blue, lid2 RMSD; black, lid1-lid2 distance.
