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| High dose combination group (180/160 µg) | Albuterol alone (180 µg) | Low dose combination group (180/80 µg) | Albuterol alone (180 µg) | |
|---|---|---|---|---|
| Total patients (no.) | 1013 | 1014 | 1054 | 1056 |
| Severe Exacerbations (no.) | 345 | 427 | 372 | 441 |
| Annualized rate (95% CI) | 0.43 (95% CI, 0.33 to 0.58) | 0.58 (95% CI, 0.44 to 0.77) | 0.48 (95% CI, 0.37 to 0.63) | 0.48 (95% CI, 0.37 to 0.63) |
