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. 2005 Aug 5;102(33):11757–11762. doi: 10.1073/pnas.0500937102

Fig. 2.

Fig. 2.

cnk-1 phenotypes in lin-45 raf mutant backgrounds. cnk-1(sv39) (A, C, and E) and lin-45(ku112) (30) mutants appear to be phenotypically normal, but cnk-1(sv39); lin-45(ku112) double mutants (B, D, and F) display strong Ras-like phenotypes. Differential interference contrast images of normal L1 larva (A) (ph, pharynx; int, intestine; go, gonad), rod-like lethal larva (B) (arrow marks fluid accumulation, which compresses the internal organs), normal P11.p (arrow), and P12.pa (arrowhead) cells (C), 2 P11.p (arrows) cells (D), normal L4 vulva (black arrowhead) (E), and vulvaless animal (F) (white lines mark uninduced cells). ut, uterus. cnk-1(ok836) suppresses hs-lin-45AA (G and H) but not hs-lin-45ED (I and J) Muv defects.