Fig. 2.

IFN-α2 and IFN-β exhibit the same specific activities for the induction of the expression of IFN-stimulated genes. Freshly purified monocytes from human blood donors were cultured in the presence of sRANKL and M-CSF for 2 days, and then left untreated (▵) or treated for 4 h with IFN-α2 (○) or IFN β (•). RNAs were then extracted and the levels of 6-16 (A) or 2′–5′ oligoadenylate synthetase, PKR, and MxA (B) transcripts were measured by quantitative RT-PCR. Each point in the vertical represents a different blood donor.