Table 4.

Brier score of different models for PFS at 6 months and 12 months.

Time point	Training cohort	p †	Validation cohort	p †
Models
6-Month
ADMAN	0.161	–	0.183
HAP Score	0.219	0.009	0.247	0.041
mHAP Score	0.210	0.025	0.257	0.012
mHAP-II Score	0.220	0.004	0.232	0.049
Six-and-Twelve Score	0.225	<0.001	0.214	0.238
Up-to-11 criteria	0.233	<0.001	0.244	0.047
12-Month
ADMAN	0.140	–	0.191	–
HAP Score	0.203	0.007	0.248	0.054
mHAP Score	0.202	0.014	0.240	0.049
mHAP-II Score	0.209	0.006	0.234	0.158
Six-and-Twelve Score	0.211	0.001	0.196	0.888
Up-to-11 criteria	0.215	<0.001	0.243	0.041

HAP, hepatoma arterial-embolization prognostic score; mHAP, modified hepatoma arterial-embolization prognostic score; PFS, progression-free survival.

^† p-value for comparing the brier score of ADMAN model and other prognostic model.

Bold values represent p-value < 0.05.