Table 2. Characteristics of mutations in the IgH V regions of AID-transfected hybridoma recombinants.
Cell lines | Unique mutations | CG (%) | Transitions (%) | Hotspots (% of C/G mutations) |
---|---|---|---|---|
Sp6 | 45 | 37 (82) | 26 (58) | 20 (54) |
WT | 41 | 38 (93) | 15 (37) | 28 (74) |
Eμ | 23 | 20 (87) | 17 (74) | 16 (80) |
Δ (μ+) | 61 | 59 (97) | 31 (49) | 34 (58) |