Figure 2. Both the Association Formed between New and Reactivated Information and the Reactivated Original IA Memory Are Disrupted by Systemic Inhibition of Protein Synthesis.

Latency to enter the shock chamber was taken as a measure of memory retention. Systemic anisomycin injection (Aniso, n = 8) immediately after visual CS reactivation in context B induced amnesia for both context A and B compared with vehicle injection (Veh, n = 8) (** = p < 0.01). Anisomycin did not affect memory of context A in rats that did not receive reactivation (n = 8, No-react).