Table 3. Outcome measures for diagnostic accuracy performance of POCTs.

POCT	Reference	Type of lipid measured	Diagnostic accuracy (%)
Accutrend Plus, Roche Diagnostics	Coquiero et al20	TC ☒TG ☒HDL-C ☐LDL-C ☐Non-HDL-C ☐	Diagnostic threshold (mmol/L): TC=5.17; TG=1.69TCSensitivity: 84.4Specificity: 95.2TGSensitivity: 90.5Specificity: 96.9
	Kurstjens et al43	TC ☒TG ☐HDL-C ☐LDL-C ☐Non-HDL-C ☐	Diagnostic threshold (mmol/L): TC=5.17Sensitivity: 92Specificity: 89Positive predictive value: 85Negative predictive value: 94
	Maciel et al23	TC ☒TG ☒HDL-C ☐LDL-C ☐Non-HDL-C ☐	Diagnostic threshold (mmol/L): TC=5.17; TG=1.69TCSensitivity: 100Specificity: 69.2TGSensitivity: 100Specificity: 80
Cobas b101 System, Roche Diagnostics, Switzerland	Barroso et al40	TC ☒TG ☒HDL-C ☒LDL-C ☒Non-HDL-C ☐	Threshold Cardiovascular risk>5%Male:Sensitivity, % (95% CI): 0.74 (0.63 to 0.82)Specificity, % (95% CI): 0.97 (0.95 to 0.99)Accuracy (95% CI): 0.93 (0.90 to 0.95)Female:Sensitivity, % (95% CI): 0.50 (0.30 to 0.70)Specificity, % (95% CI): 0.99 (0.98 to 1.00)Accuracy (95% CI): 0.97 (0.95 to 0.98)
Cholestech LDX, Abbott, USA	Parikh et al28	TC ☒TG ☒HDL-C ☒LDL-C ☒Non-HDL-C ☐	Diagnostic threshold (mmol/L): TC≥5.17; LDL-C1≥2.59; LDL-C2≥3.36, HDL-C<1.03; TG≥1.69TCSensitivity: 79Specificity: 95LDL-C1Sensitivity: 93Specificity: 82LDL-C2Sensitivity: 76Specificity: 92HDL-CSensitivity: 93Specificity: 78TGSensitivity: 88Specificity: 93

HDL-Chigh-density lipoprotein cholesterolLDL-Clow-density lipoprotein cholesterolPOCTpoint-of-care testingTCtotal cholesterolTGtriglyceride