Table 2.
Clinical characteristics of CLD patients treated at hospitals of Bahir Dar City, 2024 (n = 213)
| Variable | Category | Frequency | Percent |
|---|---|---|---|
| Cause of CLD | Diagnosed as: | ||
| Viral (HBV = 117, HCV = 30) | Both HBV & HCV = 6, ALD = 2 | 141 | 60.0 |
| HSS | ALD = 1, HBV = 3, HCV = 2 | 43 | 18.3 |
| ALD | HBV = 4, HCV = 1 | 27 | 11.5 |
| HMS | HCV = 4, HSS = 2 | 11 | 4.7 |
| NAFLD | 5 | 2.1 | |
| Others | TB = 2, Amoeba = 2, Drug = 4, ALD = 1 | 8 | 3.4 |
| Complications | Ascites | 138 | 64.8 |
| Portal hypertension | 114 | 52.1 | |
| Spontaneous bacterial peritonitis | 13 | 6.1 | |
| Hepatorenal syndrome | 9 | 4.2 | |
| Hepatic encephalopathy | 6 | 2.8 | |
| Comorbid condition | No | 161 | 75.6 |
| Yes* | 52 | 24.4 | |
| Stages of CLD | Compensated | 114 | 53.5 |
| Decompensated | 99 | 46.5 | |
| End stage liver disease | HCC | 60 | 60.6 |
| Cirrhosis | 39 | 39.4 | |
| Albumin level | ≥ 3.5 g/dl | 75 | 35.2 |
| < 3.5 g/dl | 138 | 64.8 | |
| APRI score | < 2 | 130 | 61.0 |
| ≥ 2 | 83 | 39.0 | |
| FIB-4 | Less likely (< 1.45) | 59 | 27.7 |
| Indeterminate (1.45–3.25) | 73 | 34.3 | |
| More likely (> 3.25 points) | 81 | 38.0 | |
|
Took appropriate treatment and regimen for specific CLD cause |
Yes | 97 | 45.5 |
| No | 116 | 54.5 | |
| Treatment duration | < 1 Years | 22 | 10.3 |
| 1–2 Years | 119 | 55.9 | |
| > 2 Years | 72 | 33.8 | |
| Clinical and serological patient outcome | Improved | 130 | 61.0 |
| Died (1 patient was on medication) | 5 | 2.4 | |
| Self-discharged (6 were on medication) | 13 | 6.1 | |
| No charge (31 took medication) | 65 | 30.5 |
Key: FIB– fibroscan, HMS - hyper-reactive malarial splenomegaly syndrome, HSS - hepatosplenic schistosomiasis, *Diabetes mellitus [9], heart failure [3], hypertension [14], pneumonia [6], renal disorder [4], tuberculosis [6], venous thromboembolism [3], HIV/AIDS [2] and others; ** no charge (66), self-discharged [13] and death [4]