Table 3.

Weighted multivariable Cox regression models to all-cause mortality

Characteristic	Model 1		Model 2		Model 3
	HR (95% CI)	P value	HR (95% CI)	P value	HR (95%CI)	P value
NHR Group
NHR Low	Refence		Refence		Refence
NHR High	2.31(1.62, 3.30)	< 0.001	2.25(1.55, 3.25)	< 0.001	1.82(1.21, 2.74)	0.004
DSST Group
Normal cognition	Refence		Refence		Refence
Cognitive impairment	2.91(1.90, 4.46)	< 0.001	2.24(1.51, 3.33)	< 0.001	1.87(1.25, 2.79)	0.002
NHR & DSST Group
NHR Low & Normal cognition	Refence		Refence		Refence
NHR High & Normal cognition	2.48(1.71, 3.58)	< 0.001	2.52(1.69, 3.77)	< 0.001	2.12(1.42, 3.17)	< 0.001
NHR Low & Cognitive impairment	3.37(2.07, 5.48)	< 0.001	2.75(1.67, 4.52)	< 0.001	2.44(1.46, 4.08)	< 0.001
NHR High & Cognitive impairment	5.54(2.99, 10.3)	< 0.001	4.29(2.25, 8.21)	< 0.001	2.98(1.45, 6.14)	0.003

HR = Hazard Ratio, CI = Confidence Interval

Model 1: no adjustment

Model 2: adjusted for Sex, Age, Race, Education attainment, PIR, Alcohol intake, Smoking

Model 3: adjusted for Model 2 plus Hypertension, Diabetes, BMI, Stroke, Cardiovascular disease, CKD