Table 3.

Effects (beta ± SE) of two diets on change in TRL particle TG from adjusted linear mixed effects regression models, stratified by TCF7L2 genotype¹

	CC Genotype				TT Genotype				P interaction2
	Diet effect (LF vs. MetD)		Order effect		Diet effect (LF vs. MetD)		Order effect
TRL triglyceride (umol/L)	Beta (SE)	P	Beta (SE)	P	Beta (SE)	P	Beta (SE)	P
XL VLDL	21.21 (10.97)	0.054	12.25 (15.11)	0.418	10.58 (7.88)	0.179	23.39 (8.83)	0.008	0.341
L VLDL	25.15 (14.56)	0.084	16.35 (20.52)	0.426	14.53 (10.25)	0.156	35.95 (10.96)	0.001	0.486
M VLDL	27.53 (16.54)	0.096	18.61 (25.02)	0.457	20.19 (11.13)	0.07	47.36 (13.68)	5.00E-04	0.671
S VLDL	9.35 (6.34)	0.14	5.03 (11.06)	0.65	9.26 (6.37)	0.146	20.63 (6.17)	8.00E-04	0.866
XS VLDL	3.01 (1.36)	0.027	0.61 (2.92)	0.834	3.91 (4.93)	0.428	3.36 (2.83)	0.236	0.806
IDL	4.65 (1.72)	0.007	2.16 (2.65)	0.415	4.42 (6.01)	0.462	1.83 (2.84)	0.521	0.912
Total TRL	82.51 (48.07)	0.082	52.43 (71.42)	0.463	54.20 (33.29)	0.104	126.56 (38.78)	0.001	0.548

Values are beta (SE) from multivariable linear regression models, adjusted for pre-treatment value, age, sex, and BMI, stratified by genotype. Bolded P-values were statistically significant at P ≤ 0.05

¹P-values are for the main effect of each variable

²P interaction - P-values for interaction between genotype and diet on TRLs