Table 2.
Univariate and multivariate regression analysis of various inflammatory indicators and COPD.
| Inflammation index | Crude model | Minimally adjusted | Fully adjusted |
|---|---|---|---|
| SIRI | |||
| Continuous | 1.516 (1.380, 1.665) < 0.001 | 1.259 (1.131, 1.401) < 0.001 |
1.350 (1.220, 1.493) < 0.001 |
| Q1 | Ref | Ref | Ref |
| Q2 | 1.279 (0.994, 1.647) 0.062 | 1.143 (0.873, 1.497) 0.329 | 1.180 (0.908, 1.532) 0.216 |
| Q3 | 1.534 (1.201, 1.960) < 0.001 | 1.209 (0.926, 1.579) 0.162 | 1.344 (1.042, 1.732) 0.023 |
| Q4 | 2.352 (1.865, 2.965) < 0.001 | 1.494 (1.154, 1.935) 0.002 | 1.836 (1.438, 2.343) < 0.001 |
| SII | |||
| Continuous | 1.001 (1.000, 1.001) < 0.001 | 1.000 (1.000, 1.001) 0.008 | 1.000 (1.000, 1.001) 0.003 |
| Q1 | Ref | Ref | Ref |
| Q2 | 1.094 (0.862, 1.388) 0.461 | 1.118 (0.865, 1.444) 0.394 | 1.169 (0.912, 1.499) 0.216 |
| Q3 | 1.261 (0.999, 1.592) 0.051 | 1.254 (0.976, 1.611) 0.077 | 1.288 (1.010, 1.642) 0.042 |
| Q4 | 1.571 (1.255, 1.968) < 0.001 | 1.436 (1.123, 1.835) 0.004 | 1.486 (1.173, 1.883) 0.001 |
| NLR | |||
| Continuous | 1.212 (1.132, 1.296) < 0.001 | 1.057 (0.985, 1.134) 0.121 | 1.130 (1.052, 1.213) < 0.001 |
| Q1 | Ref | Ref | Ref |
| Q2 | 1.253 (0.978, 1.605) 0.075 | 1.134 (0.870, 1.477) 0.353 | 1.313 (1.016, 1.698) 0.038 |
| Q3 | 1.576 (1.241, 2.001) < 0.001 | 1.368 (1.057, 1.771) 0.017 | 1.611 (1.256, 2.067) < 0.001 |
| Q4 | 1.988 (1.577, 2.506) < 0.001 | 1.350 (1.047, 1.741) 0.021 | 1.745 (1.370, 2.222) < 0.001 |
| LLR | |||
| Continuous | 1.003 (1.006, 1.007) 0.017 | 0.997 (0.994,1.000) 0.071 | 1.005 (1.003, 1.008) < 0.001 |
| Q1 | Ref | Ref | Ref |
| Q2 | 0.845 (0.670, 1.065) 0.153 | 0.862 (0.642, 1.061) 0.135 | 0.915 (0.717, 1.167) 0.473 |
| Q3 | 1.008 (0.805, 1.261) 0.948 | 0.849 (0.665, 1.082) 0.186 | 1.202 (0.948, 1.524) 0.129 |
| Q4 | 1.110 (0.891, 1.383) 0.353 | 0.735 (0.577, 0.935) 0.012 | 1.342 (1.060, 1.699) 0.014 |
| LMR | |||
| Continuous | 1.098 (1.051, 1.147) < 0.001 | 1.082 (1.030, 1.138) 0.002 | 1.047 (0.996, 1.100) 0.071 |
| Q1 | Ref | Ref | Ref |
| Q2 | 0.649 (0.522, 0.806) < 0.001 | 0.897 (0.709, 1.134) 0.363 | 0.714 (0.568, 0.896) 0.004 |
| Q3 | 0.531 (0.426, 0.661) < 0.001 | 0.908 (0.713, 1.156) 0.433 | 0.6377 (0.506, 0.802) < 0.001 |
| Q4 | 0.451 (0.361, 0.561) < 0.001 | 0.904 (0.705, 1.160) 0.428 | 0.525 (0.417, 0.663) < 0.001 |
Significant values are in bold.
Crude model: No covariates were adjusted.
Minimally adjusted: Adjusted for age, sex, race, and education level.
Fully adjusted: Adjusted for age, sex, race, education level, PIR, BMI, hypertension, diabetes, coronary heart disease, heart attack, angina, stroke, smoke status, and drinking status.