Table 2.

Clinical characteristics of COVID-19 cases among healthcare workers at a research reference center in Brazil, from October 2020 to July 2022

Clinical symptoms	SARS-CoV-2 infection
	Positive		Negative		Total		Odds ratio(OD); p- value
	N	%	N	%	N	%
Fever
No	143	26.7	393	73.3	536	63.4	2020(OR:3.1246;p:0,06); 2021 (OR:2.6070;p:0.002);
Yes	126	40.8	183	59.2	309	36.6	2022 (OR:1.4094; p:0.14)
Runny Nose
No	96	27.6	252	72.4	348	41.2	2020(OR:1.1690;p:0.68); 2021(OR:0.4857;p:0.05);
Yes Nasal	173	34.8	324	65.2	497	58.8	2022 (OR:2.7986; p:0.0001)
obstruction
No	181	30.4	415	69.3	596	70.5	2020(OR:0.5037;p:0.23); 2021(OR:1.2018;p:0.48);
Yes	89	35.7	160	64.3	249	29.5	2022(OR:1.7882; p:0.06)
Arthralgia
No	248	31.1	549	68.9	797	94.3	2020(OR:4.2759;p:0.02); 2021(OR:2.7143;p:0.03);
Yes	22	45.8	26	54.2	48	5.7	2022 (OR:0.0396; p:089)
Myalgia
No	201	31.5	437	68.5	638	75.5	2020(OR:2.2042;p:0.06); 2021(OR:0.8000;p:0.45);
Yes	69	33.3	138	66.7	207	24.5	2022 (OR:1.1916;p:0.51)
Cough
No	65	20.4	253	79.6	318	37.6	2020(OR:2.1529;p:0.06); 2021(OR:1.6667;p:0.05);
Yes	205	38.9	322	61.1	527	62.4	2022 (OR:2.8085; p:0.0001)
Headache
No	144	32.3	302	67.7	446	52.7	2020(OR:0.6682;p:0.30); 2021(OR:0.8435;p:0.50);
Yes	126	31.6	273	68.4	399	47.3	2022 (OR:1.2911; p:0.26)
Sore throat
No	87	30.1	202	69.9	289	34.2	2020(OR:0.9190;p:0.82); 2021(OR:1.2868;p:0.38);
Yes	183	33.0	373	67.0	556	65.8	2022(OR:1.2460, p:0.41)
Chills
No	203	28.0	522	72.0	725	85.8	2020(OR:9.000;p:0.002); 2021(OR:2.1750;p:0.01);
Yes	67	55.8	53	44.2	120	14.2	2022 (OR:3.6056; p:0.0001)
Dyspneia
No	251	32.0	534	68.0	785	92.9	2020(OR:0.4583;p:0.46); 2021(OR:1.6182;p:0.19);
Yes	19	31.7	41	68.3	60	7.1	2022 (OR:1.9211; p:0.34)
Diarrhea
No	229	32.9	468	67.1	697	82.5	2020(OR:2.6065;p:0.02); 2021(OR:0.8182;p:0.56);
Yes	41	27.7	107	72.3	148	17.5	2022(OR:1.1486; p:0.70)

^*Logistic regression test