Table 2.
A summary of the effects of SDF-1/CXCR4 in tissue repair and regeneration according to various authors
| Effect of SDF-1/CXCR4 in tissue repair and regeneration | Reference |
|---|---|
| Recruitment of stem and progenitor cells to damaged area | Yuan et al. 2013 |
| Homeostatic regulation of white blood cell trafficking, organ development, and tissue repair | Haque et al. 2020 |
| Promotion of directional migration of cells and organ regeneration | Haque et al. 2020 |
| Modulation of muscle repair dependent on MMP-10 activity | Bobadilla et al. 2014 |
| Enhancement of skeletal muscle regeneration and stem cell recruitment to damaged muscles with increase CD9 expression | Brzoska et al. 2015 |
| Increase in production of key trophic factors like FGF, HGF, IGF, NGF, and VEGF for tissue repair | Zisa et al. 2011 |