Table 3.
Subgroup analysis of the association between blood ethylene oxide levels and serum neurofilament light chain.
| Subgroup | HbEO (pmol/g Hb) | Q3 OR (95% CI) | P for interaction | |
|---|---|---|---|---|
| Q1 OR (95% CI) | Q2 OR (95% CI) | |||
| Gender | 0.7921 | |||
| Male | 1.00 | 0. 18 (0.02, 0.34) | 0.26 (0.09, 0.43) | |
| Female | −1.25 (−2.03, −0.46) | −1. 10 (−1.87, −0.32) | −0.93 (−1.70, −0. 16) | |
| Race/ethnicity | 0.1659 | |||
| Mexican American | 1.00 | 0.08 (−0.26, 0.43) | −0. 17 (−0.70, 0.35) | |
| Other Hispanic | −0.01 (−2. 14, 2. 12) | 0.34 (−1.83, 2.51) | 0.41 (−1.77, 2.60) | |
| Non-Hispanic white | 0.26 (−1.31, 1.84) | 0.43 (−1. 14, 2.01) | 0.62 (−0.95, 2. 19) | |
| Non-Hispanic black | −0.82 (−2.72, 1.07) | −1. 15 (−3.04, 0.74) | −1.03 (−2.87, 0.82) | |
| Other race | 0. 17 (−2.29, 2.64) | 0.36 (−2.02, 2.74) | 0.21 (−2.20, 2.62) | |
| Education level | 0.0389 * | |||
| Less than 9th grade | 1.00 | −0.06 (−0.68, 0.55) | 0.03 (−0.65, 0.71) | |
| 9-11th grade | 1. 10 (−1.20, 3.41) | 1. 16 (−1. 16, 3.48) | 1.04 (−1. 19, 3.27) | |
| High school graduate | 0.24 (−1.76, 2.24) | 0.88 (−1.09, 2.85) | 0.63 (−1.36, 2.63) | |
| Some college or AA degree | 0.08 (−1.85, 2.01) | 0. 17 (−1.76, 2. 10) | 0.28 (−1.65, 2.21) | |
| College graduate or above | 1.22 (−0.77, 3.21) | 1.26 (−0.73, 3.25) | 1.48 (−0.50, 3.46) | |
| High blood pressure | 0.5993 | |||
| Yes | 1.00 | 0. 19 (−0.03, 0.42) | 0.37 (0. 16, 0.57) | |
| No | −0.06 (−0.96, 0.84) | 0.08 (−0.82, 0.98) | 0. 18 (−0.72, 1.08) | |
| High cholesterol level | 0.8619 | |||
| Yes | 1.00 | 0. 13 (−0.07, 0.32) | 0.21 (−0.01, 0.44) | |
| NO | 0. 11 (−0.78, 1.00) | 0.27 (−0.62, 1. 16) | 0.40 (−0.49, 1.28) | |
| Diabetes | 0.4778 | |||
| Yes | 1.00 | −0.05 (−0.47, 0.37) | −0.02 (−0.55, 0.51) | |
| No | −0.08 (−1.83, 1.67) | 0.08 (−1.67, 1.83) | 0.21 (−1.54, 1.96) | |
| Alcohol use | 0.4448 | |||
| Yes | 1.00 | 0. 16 (0.03, 0.29) | 0.31 (0. 18, 0.44) | |
| No | −0. 12 (−1.06, 0.81) | 0.01 (−0.93, 0.96) | −0.03 (−0.95, 0.89) | |
| BMI (kg/m2) | 0.1282 | |||
| <25.0 | 1.00 | 0.27 (0.06, 0.47) | 0.44 (0.21, 0.67) | |
| ≥25.0 | 0.73 (−0.26, 1.72) | 0.83 (−0. 16, 1.82) | 0.91 (−0.08, 1.90) | |
| PIR | 0.0158* | |||
| <1.3 | 1.00 | 0.24 (−0.03, 0.50) | 0.21 (−0.04, 0.46) | |
| ≥1.3, <3.5 | 0.43 (−0.62, 1.48) | 0.59 (−0.48, 1.65) | 0.96 (−0.08, 2.00) | |
| ≥3.5 | 0.55 (−0.37, 1.46) | 0.72 (−0. 18, 1.62) | 0.67 (−0.26, 1.60) | |
95% CI, 95% confidence interval; OR, odds ratio; PIR, poverty income ratio; BMI, body mass index. The strata variable was not included when stratifying by itself. *Symbol to indicate some groups that are statistically significant and contribute to the argument of the article’s results for ease of reading.