. 2025 Mar 7;97(3):e70278. doi: 10.1002/jmv.70278

Table 3.

Characteristics of enrolled head and neck cancer patients (n = 132) stratified by sex, age, and anatomical sites, oropharyngeal cancer (OPC) and non‐oropharyngeal cancer (non‐OPC) head and neck cancer site according to HPV marker detected by beads‐based Luminex assay (E7‐MPG).

		Sex			Age			Site
	HPV status	M (n)	F (n)	p value^a	< 60 (n)	> 60 (n)	p value^a	OPC (n)	Non‐OPC^b (n)	p value^a
HPV DNA marker
ctHPV DNA (plasma)	Negative (n)	81	34	0.04	40	75	0.06	10	105	< 0.001
	Positive (n)	16	1		10	7		13	4
Oral HPV DNA (gargle)^c	Negative (n)	72	31	0.14	37	66	0.38	6	97	< 0.001
	Positive (n)	24	4		13	15		17	11
Oral HPV DNA (swab)	Negative (n)	89	33	1.00	45	77	0.50	17	105	0.002
	Positive (n)	8	2		5	5		6	4
HPV DNA FFPE Tissue^d	Negative (n)	46	20	0.01	26	40	0.80	4	62	< 0.001
	Positive (n)	22	1		10	13		10	13

Abbreviation: OPC, oropharyngeal cancer.

^{^a}

Two‐sided Fisher's Exact test.

^{^b}

Occult tumor has been included in the non‐OPC group.

^{^c}

One gargle sample not available.

^{^d}

One FFPE Tissue beta‐globin negative sample has been excluded from the analysis.