Skip to main content
. Author manuscript; available in PMC: 2025 Mar 8.
Published in final edited form as: J Thorac Cardiovasc Surg. 2023 Jul 25;166(5):e332–e376. doi: 10.1016/j.jtcvs.2023.07.023

TABLE E1.

Results of mixed effects model for denoted variables with respect to aortic segment, patient group (Marfan syndrome, Loeys-Dietz syndrome, no aortopathy), and interaction term (segment × group)

Regurgitant fraction
Fixed effects (type III) P value P value summary Statistically significant (P < .05)? F (DFn, DFd) Geisser-Greenhouse’s epsilon

Segment .009 ** Yes F (2.274, 22.74) = 5.505 0.3791
Genotype .9229 Ns No F (2, 10) = 0.08092
Segment × genotype .3306 Ns No F (12, 60) = 1.162

Wall shear stress
Fixed effects (type III) P value P value summary Statistically significant (P < .05)? F (DFn, DFd) Geisser-Greenhouse’s epsilon

Segment .0328 * Yes F (2.144, 21.44) = 3.926 0.3573
Genotype .0361 * Yes F (2, 10) = 4.714
Segment × genotype .0131 * Yes F (12, 60) = 2.399

Peak velocity
Fixed effects (type III) P value P value summary Statistically significant (P < .05)? F (DFn, DFd) Geisser-Greenhouse’s epsilon

Segment .0254 * Yes F (1.612, 16.12) = 5.042 0.2686
Genotype .037 * Yes F (2, 10) = 4.667
Segment × genotype .0296 * Yes F (12, 60) = 2.108
*

P < .05

**

P < .01