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. 2025 Feb 28;11:e2702. doi: 10.7717/peerj-cs.2702

Table 1. Summary of Hyperledger fabric and ML integrated literatures.

Ref Domain adopted Implemented blockchain ML models used Metrics Dataset Shortcomings
Hu & Kar (2024) Health monitoring system Hyperledger fabric ModelChain Throughput, model accuracy No Two blockchains increases the complexity and overhead. Scalability challenges.
Sasikumar & Karthikeyan (2023) Healthcare (cardiovascular disease severity identification) Hyperledger consortium Naïve Bayes Throughput, latency Yes The ML component has been unevaluated and it has been incorporated into the Chaincode, possibly elevating system complexity.
Sharma & Rohilla (2023) Drug discovery chain management Hyperledger fabric No details Throughput, latency No Exclusively utilized ML for visualization of data and preliminary processing, without applying any specific algorithms.
Heidari et al. (2023) Healthcare (Lung cancer detection) No details Federated learning Accuracy, precision, recall, F1 score Yes Lack of transparency in blockchain part and limited interpretability,
Bharimalla et al. (2021) Electronic health record system Hyperledger fabric Natural Language Processing (NLP) Accuracy, throughput, latency No The focus is only on the digital transformation of prescriptions and there is no extensive information about the dataset used.
Pandey et al. (2022) Waste identification and reuse idea recommending system Hyperledger fabric ResNet50 Accuracy, latency Yes For reuse idea recommendation system, blockchain integration increases complexity