Table 3.
Partial correlation between cortical thickness measures in different regions of the adolescent brains and maternal EDCs measures in adolescent mothers, controlling for sex, family income, and urinary creatinine.
| EDCs | Cortical Indices | Region | r | P-value | Covariates |
|---|---|---|---|---|---|
| All adolescent mothers | |||||
| Cord Blood | |||||
| PFDeA | Surface Area | Left postcentral gyrus | 0.458 | <0.001 | Sex + Family income |
| Urine | |||||
| MEHP | Cortical thickness | Right superior parietal cortex | 0.442 | <0.001 | Sex + Family income + Urinary creatinine |
| Mothers with male adolescents | |||||
| Cord Blood | |||||
| PFOA | Cortical thickness | Right inferior frontal gyrus (pars triangularis) | −0.655 | <0.001 | Family income |
| PFDeA | Surface Area | Left rostral anterior cingulate cortex | 0.549 | <0.001 | |
| Urine | |||||
| MBP | Surface Area | Right rostral anterior cingulate cortex | −0.640 | <0.001 | Family income + Urinary creatinine |
| MEHP | Cortical thickness | Right lingual gyrus | 0.467 | <0.001 | |
| Cortical thickness | Right superior parietal cortex | 0.536 | <0.001 | ||
| Mothers with female adolescents | |||||
| No significant results | |||||
| EDC: endocrine-disrupting chemicals. PFOA: perfluorooctanoic acid. PFDeA: perfluorodecanoic acid. MEHP: mono-2-ethylhexyl phthalate. MBP: mono-butyl phthalate. | |||||