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. 2005 Aug 19;1(2):e23. doi: 10.1371/journal.pgen.0010023

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Copyright: © 2005 Tolwani et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Serum acylcarnitine analysis of MCAD^+/+ (n = 4) and MCAD^−/− mice (n = 4)

There are significant elevations in acylcarnitine species as indicated in MCAD^−/− mice. Values shown are mean values ± standard deviation (SD). Asterisk indicates p < 0.002 and ‡ indicates p < 0.01.

(B) There are significant elevations in bile acylcarnitines of the same mice shown in (A) as indicated. Values shown are mean values ± SD. Asterisk indicates p < 0.001.

(C) Bile acylcarnitine profile of an MCAD^−/− mouse compared to a human patient with MCAD deficiency. Internal standards are indicated by an asterisk.