Skip to main content
. 2025 Feb 24;12:1503142. doi: 10.3389/fmed.2025.1503142

Table 1.

Baseline characteristics of the selected participants.

Characteristic Sex p-value
Overall, N = 2,617 Female, N = 1,323 Male, N = 1,294
Age 56 (47, 65) 56 (47, 65) 56 (48, 65) 0.680
Race/ethnicity 0.772
Mexican American 364 (13.9%) 180 (13.6%) 184 (14.2%)
Non-Hispanic Black 488 (18.6%) 254 (19.2%) 234 (18.1%)
Non-Hispanic White 1,346 (51.4%) 687 (51.9%) 659 (50.9%)
Other Hispanic 270 (10.3%) 132 (10.0%) 138 (10.7%)
Other Race 149 (5.7%) 70 (5.3%) 79 (6.1%)
Education Level 0.113
Above high school 1,414 (54.0%) 739 (55.9%) 675 (52.2%)
High school or GED 588 (22.5%) 293 (22.1%) 295 (22.8%)
Less than high school 615 (23.5%) 291 (22.0%) 324 (25.0%)
Marital status <0.001
Divorced, separated, or widowed 692 (26.4%) 435 (32.9%) 257 (19.9%)
Married or cohabiting 1,708 (65.3%) 770 (58.2%) 938 (72.5%)
Unmarried 217 (8.3%) 118 (8.9%) 99 (7.7%)
PIR 0.070
Low [0,1.65] 866 (33.1%) 462 (34.9%) 404 (31.2%)
Medium [1.65,4.04] 877 (33.5%) 443 (33.5%) 434 (33.5%)
High [4.04,5] 874 (33.4%) 418 (31.6%) 456 (35.2%)
Body mass index (kg/m2) <0.001
< 25 640 (24.5%) 356 (26.9%) 284 (21.9%)
≥ 30 1,033 (39.5%) 574 (43.4%) 459 (35.5%)
25–30 944 (36.1%) 393 (29.7%) 551 (42.6%)
HRR <0.001
Low [0.26,1.06] 870 (33.2%) 645 (48.8%) 225 (17.4%)
Medium [1.06,1.18] 873 (33.4%) 500 (37.8%) 373 (28.8%)
High [1.18,1.58] 874 (33.4%) 178 (13.5%) 696 (53.8%)
Smoking history <0.001
No 1,304 (49.8%) 758 (57.3%) 546 (42.2%)
Yes 1,313 (50.2%) 565 (42.7%) 748 (57.8%)
High blood pressure 0.761
No 1,470 (56.2%) 747 (56.5%) 723 (55.9%)
Yes 1,147 (43.8%) 576 (43.5%) 571 (44.1%)
Drinking history <0.001
No 653 (25.0%) 469 (35.4%) 184 (14.2%)
Yes 1,964 (75.0%) 854 (64.6%) 1,110 (85.8%)
Respiratory illness 0.361
No 2,113 (80.7%) 1,059 (80.0%) 1,054 (81.5%)
Yes 504 (19.3%) 264 (20.0%) 240 (18.5%)
Glycohemoglobin (%) 5.60 (5.30, 6.00) 5.60 (5.30, 6.00) 5.60 (5.30, 6.00) 0.324
Albumin (g/dL) 4.20 (4.00, 4.40) 4.20 (4.00, 4.30) 4.30 (4.10, 4.40) <0.001
ALT (U/L) 22 (17, 29) 20 (16, 25) 25 (20, 33) <0.001
AST (U/L) 24 (20, 28) 22 (19, 27) 25 (22, 30) <0.001
Creatinine (μmol/L) 74 (64, 88) 66 (58, 75) 84 (74, 95) <0.001
Uric acid (mg/dL) 5.50 (4.60, 6.40) 4.90 (4.10, 5.80) 6.00 (5.30, 6.80) <0.001
Fasting Glucose (mg/dL) 102 (95, 113) 100 (93, 109) 104 (97, 116) <0.001
Insulin (uU/mL) 10 (7, 16) 10 (6, 16) 11 (7, 17) 0.101
Lymphocyte number (1,000 cells/uL) 1.90 (1.50, 2.30) 1.90 (1.60, 2.30) 1.80 (1.50, 2.20) <0.001
Monocyte number (1,000 cells/uL) 0.50 (0.40, 0.60) 0.50 (0.40, 0.60) 0.50 (0.40, 0.60) <0.001
White blood cell count (1,000 cells/uL) 6.30 (5.30, 7.60) 6.20 (5.10, 7.60) 6.30 (5.30, 7.60) 0.124
HGB (g/dL) 14.30 (13.30, 15.20) 13.60 (12.70, 14.30) 15.10 (14.30, 15.90) <0.001
Red cell distribution width (%) 12.70 (12.30, 13.30) 12.70 (12.30, 13.50) 12.70 (12.30, 13.30) 0.011
Platelet count (1,000 cells/uL) 238 (201, 283) 254 (216, 299) 224 (190, 259) <0.001
LDL-cholesterol (mg/dL) 118 (96, 142) 120 (99, 144) 116 (94, 140) 0.008
Waist Circumference (cm) 100 (91, 110) 97 (88, 108) 102 (94, 112) <0.001
FVC 8.19 (7.98, 8.39) 8.02 (7.86, 8.17) 8.38 (8.23, 8.50) <0.001
FEV1 7.91 (7.70, 8.11) 7.75 (7.59, 7.91) 8.09 (7.92, 8.24) <0.001
PEF 8.93 (8.74, 9.13) 8.79 (8.62, 8.92) 9.12 (8.96, 9.25) <0.001
PEF 25–75% 7.75 (7.38, 8.06) 7.64 (7.30, 7.92) 7.89 (7.49, 8.19) <0.001