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. 2025 Feb 24;16:1544154. doi: 10.3389/fimmu.2025.1544154

Table 3.

Univariate and multivariate Cox analysis: correlation between signal sequence receptor subunit delta (SSR4) expression and the clinical characteristics of esophageal squamous cell carcinoma (ESCC) patients.

Clinical factors Univariate cox Multivariate cox
HR (95%CI) P HR (95%CI) P
Gender 1.661 (0.720,3.831) 0.234
Age 3.059 (1.517,6.172) 0.002 3.275 (1.588,6.753) 0.001
Morphology 0.984 (0.747,1.203) 0.659
Lymph node
metastatic
2.882
(1.395,5.951)
0.004 1.507
(0.295,7.703)
0.623
Lymph node
metastatic ratio
34.132
(7.241,160.901)
<0.001 21.582
(1.466,317.765)
0.025
T stage 0.908 (0.476,1.732) 0.770
N stage 2.876 (1.391,5.943) 0.004 0.973 (0.297,3.188) 0.964
M stage 3.537 (0.481,26.038) 0.215
AJCCTNM 2.640 (1.312,5.312) 0.006 0.864 (0.179,4.160) 0.855
SSR4 2.271 (1.128,4.573) 0.022 1.507 (0.637,3.566) 0.351

Italic fonts indicate statistically significant.