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. 2025 Feb 20;9(2):100590. doi: 10.1016/j.mayocpiqo.2025.100590

Table 2.

Common State Qualifying Conditions for Medical Cannabis that Were Deemed Partial Because of Broad Wording, Compared With Evidence Found by NAS11

Qualifying Condition NAS Evidence Related to This Condition
Anxiety Limited evidence for: anxiety symptoms in those with social anxiety.
Cachexia Limited evidence for: increased appetite and decreased weight loss in HIV/AIDS. Insufficient evidence for: anorexia/cachexia syndrome in cancer.
Cancer Conclusive/substantial evidence of effectiveness for: long-term pain in cancer, chemotherapy-induced nausea and vomiting.Insufficient evidence for: cancer regression, cancer-associated anorexia/cachexia syndrome.
HIV or AIDS Limited evidence of effectiveness for: increased appetite and decreased weight loss in HIV/AIDS.
Multiple sclerosis Substantial evidence for: patient-reported MS spasticity, long-term pain due to MS. Moderate evidence for: improved short-term sleep outcomes for MS. Limited evidence for: clinician-measured MS spasticity. Limited evidence of ineffectiveness for: depressive symptoms due to MS.
Nausea Conclusive evidence for: chemotherapy-induced nausea and vomiting.
Seizure Insufficient evidence for: epilepsy.
Severe and persistent muscle spasms Substantial evidence for: patient-reported MS spasticity. Limited evidence for: clinician-measured MS spasticity.Insufficient evidence for: spasticity due to paralysis due to spinal cord injury, dystonia, Parkinson's disease motor system symptoms, or levodopa-induced dyskinesia.

MS, multiple sclerosis; NAS, National Academy of Sciences.