Table 5.
Risk Classes and Predicted Probabilities of NSAID-Induced Cardiovascular Events
| Risk Class | Risk Index Score (Points) | All Patients (n=2551637), n(%)* | Average Predicted Probability (95% CI) | Observed Incidence |
|---|---|---|---|---|
| 1 | 0–50 | 1,811,997 (71.0) | 0.03 (0.03, 0.03) | 0.02 |
| 2 | 51–58 | 409,312 (16.0) | 0.14 (0.14, 0.14) | 0.14 |
| 3 | 59–63 | 137,973 (5.4) | 0.24 (0.24, 0.24) | 0.26 |
| 4 | 64–68 | 77,499 (3.0) | 0.34 (0.34, 0.34) | 0.39 |
| 5 | 69–72 | 37,932 (1.5) | 0.46 (0.46, 0.46) | 0.49 |
| 6 | 73–76 | 27,188 (1.1) | 0.55 (0.55, 0.55) | 0.55 |
| 7 | 77–80 | 18,131 (0.7) | 0.65 (0.65, 0.65) | 0.60 |
| 8 | 81–85 | 15,088 (0.6) | 0.74 (0.74, 0.74) | 0.64 |
| 9 | 86–93 | 11,443 (0.4) | 0.84 (0.83, 0.84) | 0.69 |
| 10 | ≥94 | 5,074 (0.2) | 0.93 (0.93, 0.93) | 0.75 |
Notes: *Percentage total not equal to 100 due to rounding. Model Performance. C-Statistic=0.88.