Fig. 2.

Position vs. time from representative Monte Carlo simulations at [ATP] = 400 μM and [ATP] = 1 mM. For dynein, the following values were used in the simulations and apply to all of the dynein figures that follow. We take the optical trap stiffness k_trap = 0.007 pN·nm^–1 as in ref. 18. d₀ = 6 nm, α = 0.3, β = 0.7, and p_syn = 0.23. The rate constants have the values , , M^–1·s^–1, , , , and .