Table 2. Association between susceptibility to pediatric tuberculosis disease and NRAMP1 alleles stratified by family structure.

		Simplex families				Multiplex families
			P value				P value
Gene	Polymorphism	Informative families	fbat	rc-tdt	Conditional logistic regression	Informative families	fbat*	rc-tdt†	Conditional‡ logistic regression
NRAMP1	N01	39	0.020	0.048	ND	22	0.594	0.697	ND
	N02	36	0.00045	0.00059	0.00080	19	1.000	1.000	ND
	N03	37	0.014	0.021	ND	17	0.7546	0.876	ND

^*FBAT, Family Based Association Test (33).

^†RC-TDT, Reconstruction-Combined TDT (35).

^‡ND, not done.