Table S4. IHC score of ERK1/2.
| Patient code | Recurrence group | ERK1/2 | SNF subtype |
| IHC, immunohistochemical; SNF, similarity network fusion. | |||
| PEYS | No relapse | 0 | SNF2 |
| ZLPB | No relapse | 0 | SNF2 |
| KELR | Primary resistant | 10 | SNF3 |
| UKMR | Primary resistant | 0 | SNF2 |
| UBSN | No relapse | 0 | SNF3 |
| NUVQ | No relapse | 0 | SNF4 |
| NVIY | No relapse | 0 | SNF4 |
| AYKR | No relapse | 0 | SNF2 |
| SAEI | No relapse | 0 | SNF1 |
| PBLW | No relapse | 0 | SNF2 |
| GTNE | No relapse | 0 | SNF1 |
| COUE | No relapse | 0 | SNF3 |
| XPVH | No relapse | 0 | SNF4 |
| TOCM | No relapse | 0 | SNF3 |
| NIDW | No relapse | 0 | SNF3 |
| IEQH | No relapse | 0 | SNF2 |
| XKIR | No relapse | 0 | SNF3 |
| XSJM | No relapse | 0 | SNF3 |
| ZPWX | Secondary resistant | 5 | SNF1 |
| JLWB | No relapse | 0 | SNF3 |
| LWBT | No relapse | 0 | SNF1 |
| BTJD | No relapse | 0 | SNF1 |
| TLKM | No relapse | 0 | SNF1 |
| WVAK | No relapse | 0 | SNF3 |
| LRZM | No relapse | 0 | SNF2 |
| QWJP | No relapse | 0 | SNF3 |
| FWMQ | No relapse | 0 | SNF2 |
| COUB | Secondary resistant | 30 | SNF2 |
| QAGJ | No relapse | 0 | SNF1 |
| PHRN | No relapse | 0 | SNF3 |
| MNXT | No relapse | 0 | SNF2 |
| ZRXI | No relapse | 0 | SNF3 |
| WRNK | No relapse | 0 | SNF1 |
| QLHW | No relapse | 0 | SNF4 |
| FENY | No relapse | 0 | SNF1 |
| YIGX | No relapse | 0 | SNF2 |
| HAIV | No relapse | 0 | SNF3 |
| QGCM | Primary resistant | 5 | SNF2 |
| QLJI | No relapse | 0 | SNF3 |
| JTUY | Endocrine sensitive | 0 | SNF2 |
| JLDQ | No relapse | 0 | SNF3 |
| ICKO | Endocrine sensitive | 1 | SNF3 |
| NBPH | No relapse | 1 | SNF1 |
| YJDI | Primary resistant | 8 | SNF1 |
| FQCZ | Secondary resistant | 5 | SNF4 |
| VPHD | Secondary resistant | 0 | SNF3 |
| GQCV | Primary resistant | 4 | SNF3 |
| NXYB | Endocrine sensitive | 0 | SNF1 |
| TXRL | No relapse | 4 | SNF1 |
| WYJE | Primary resistant | 5 | SNF2 |
| VEBY | No relapse | 4 | SNF1 |
| OPBQ | No relapse | 4.5 | SNF1 |
| EVNI | Endocrine sensitive | 15 | SNF4 |
| NVIW | No relapse | 5 | SNF2 |
| EFWC | No relapse | 5 | SNF2 |
| XMIT | No relapse | 5 | SNF2 |
| VBIT | No relapse | 5 | SNF1 |
| CLAV | No relapse | 5 | SNF2 |
| UWIR | Secondary resistant | 4 | SNF3 |
| INMG | No relapse | 5 | SNF2 |
| MBAU | No relapse | 5 | SNF2 |
| ORNF | Primary resistant | 4 | SNF3 |
| UPLH | No relapse | 7 | SNF1 |
| VQKJ | Endocrine sensitive | 15 | SNF3 |
| TBSH | No relapse | 8 | SNF1 |
| ZIAO | No relapse | 8 | SNF1 |
| SPTV | No relapse | 10 | SNF1 |
| YENU | No relapse | 10 | SNF2 |
| IZVH | No relapse | 10 | SNF1 |
| KBPY | Secondary resistant | 20 | SNF1 |
| RNCI | No relapse | 10 | SNF3 |
| MNDC | No relapse | 10 | SNF2 |
| KCIF | No relapse | 10 | SNF1 |
| LASO | No relapse | 15 | SNF1 |
| WEPS | Secondary resistant | 15 | SNF3 |
| WDRH | No relapse | 25 | SNF2 |