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ISO improved the depression-like behaviors and histopathological changes in CUMS mice. The schedule of the experiments (A). Result of Sucrose preference (B) and total liquid intake (C) in SPT. Result of Immobility time (D) and Climbing time (E) of FST. The histopathological changes in hippocampus of mice (F), and arrow points to nuclear retraction. n=10/group; *p<0.05 vs. Con group; **p<0.01 vs. Con group; #p<0.05 vs. Mod group; ##p<0.01 vs Mod group.
