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. 2005 Jun 29;6:165. doi: 10.1186/1471-2105-6-165

Table 1.

Comparisons of t- and deviance tests in overdispersed logistic regression and log-linear models and a test based on a Bayesian model

Group 1a logistic regression log-linear model Bayesian model
library 1 library 2 t-testc deviance test t-testc deviance test Ed




1b 0 0 0.645 0.115 0.003 0.001 0.01
2 2 2 0.485 0.122 0.002 0.002 0.02
3 5 5 0.383 0.133 0.003 0.005 0.04
4 10 10 0.324 0.149 0.007 0.01 0.05
5 20 20 0.291 0.183 0.02 0.025 0.07
6 50 50 0.324 0.29 0.104 0.117 0.11
7 100 100 0.494 0.508 0.376 0.404 0.12

aTag counts in group 1 are artificially increased towards the levels observed in group 2 (which are held fixed). Tag counts in group 2 are 312, 549, 246, 65, 41, and 52. The library sizes and tag counts in group 2 are taken from Baggerly et al. [15].

b The empirical tag counts 0.506, and 0.494 are used to replace the zero counts in group 1[15].

c The t-test here is testing the hypothesis that β = 0.

d E, the Bayes Error Rate, is listed. [26].